Issue 7, 2024

An isotope dilution mass spectrometry overview: tips and applications for the measurement of radionuclides

Abstract

This article proposes a practical guide including good laboratory practices followed by a critical review about the application of isotope dilution mass spectrometry (ID-MS) measurement to radionuclide analyses. Several national and international scientific institutions (French Alternative Energies and Atomic Energy Commission, French Radioprotection and Nuclear Safety Institute, European Commission, International Atomic Energy Agency, and Belgian Nuclear Research Centre) participated in this review by sharing their good laboratory practices. ID-MS is one of the primary ratio methods of measurement in the International System of Units. It can produce highly accurate results, as potential sources of bias can be controlled. Many hints are given to obtain the best performance. In addition, a script written with the open source software Octave is provided to calculate the optimal parameters of the {sample–spike} mixture easily. Radionuclide analysis by ID-MS applies to many different fields (environmental, biological, reference materials, irradiated samples, process control, nuclear safeguards and nuclear forensics).

Graphical abstract: An isotope dilution mass spectrometry overview: tips and applications for the measurement of radionuclides

Supplementary files

Article information

Article type
Critical Review
Submitted
26 Jan 2024
Accepted
18 Apr 2024
First published
06 May 2024
This article is Open Access
Creative Commons BY-NC license

J. Anal. At. Spectrom., 2024,39, 1665-1699

An isotope dilution mass spectrometry overview: tips and applications for the measurement of radionuclides

A. Quemet, A. Hubert, A. Gourgiotis, A. M. Sánchez Hernández, M. Crozet, G. Bailly, A. Dobney, G. Duhamel, J. Hiess, U. Repinc, S. Mialle, B. Boulet, R. Escoube, C. Bouvier-Capely, F. Pointurier and S. Picart, J. Anal. At. Spectrom., 2024, 39, 1665 DOI: 10.1039/D4JA00029C

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. You can use material from this article in other publications, without requesting further permission from the RSC, provided that the correct acknowledgement is given and it is not used for commercial purposes.

To request permission to reproduce material from this article in a commercial publication, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party commercial publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements