Issue 12, 2024

Turning Pd-catalysed direct C–H arylation of thiophene derivatives into green : industrial wastewater as an effective reaction medium

Abstract

The Pd-catalysed direct C–H arylation of thiophene derivatives, appealing for technological application, is performed under green conditions using water as the sole reaction medium. The reaction is independent of the grade of the water, thus enabling the virtuous repurposing of low-purity grade industrial wastewater, allowing one to bring the process to the gram scale and improve its green metrics.

Graphical abstract: Turning Pd-catalysed direct C–H arylation of thiophene derivatives into green : industrial wastewater as an effective reaction medium

Supplementary files

Article information

Article type
Communication
Submitted
06 Mar 2024
Accepted
28 May 2024
First published
29 May 2024
This article is Open Access
Creative Commons BY license

Green Chem., 2024,26, 7013-7018

Turning Pd-catalysed direct C–H arylation of thiophene derivatives into green : industrial wastewater as an effective reaction medium

S. Nejrotti, B. Centrella, D. Gallo, C. Barolo and M. Bonomo, Green Chem., 2024, 26, 7013 DOI: 10.1039/D4GC01139B

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