Issue 27, 2024
From the journal:

Dalton Transactions

A Pt nanoenzyme- and BODIPY-loaded nanoscale covalent organic framework for relieving intratumoural hypoxia to enhance photodynamic therapy†

Kai-Xuan Zhang,‡a   Bo Wang,‡a   Wen-Yan Li,a   Yang Song,a   Tian Song,a   Yan-An Li ORCID logo *a  and  Yu-Bin Dong ORCID logo *a  

* Corresponding authors

a College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Normal University, Jinan 250014, P. R. China
E-mail: yananli@sdnu.edu.cn, yubindong@sdnu.edu.cn

Abstract

Herein, we report a composite COF material loaded with a Pt nanoenzyme and an organic photosensitizer BODIPY, synthesized via a stepwise post-synthetic modification. The obtained Pt@COF-BDP nanoparticles can efficiently and continuously convert H2O2 to O2, thereby increasing the efficiency of single-linear oxygen production and achieving efficient tumor inhibition.

Graphical abstract: A Pt nanoenzyme- and BODIPY-loaded nanoscale covalent organic framework for relieving intratumoural hypoxia to enhance photodynamic therapy

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/D4DT00999A
Article type
Communication
Submitted
04 Apr 2024
Accepted
19 Jun 2024
First published
25 Jun 2024

Dalton Trans., 2024,53, 11242-11246

Permissions

Request permissions

A Pt nanoenzyme- and BODIPY-loaded nanoscale covalent organic framework for relieving intratumoural hypoxia to enhance photodynamic therapy

K. Zhang, B. Wang, W. Li, Y. Song, T. Song, Y. Li and Y. Dong, Dalton Trans., 2024, 53, 11242 DOI: 10.1039/D4DT00999A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements