Construction of cationic meso-thiazolium-BODIPY AIE fluorescent probes for viscosity imaging in dual organelles

Yu-Xin Tang; Yingmei Cao; Wen-Jing Shi; Jin-Cheng Li; Wei-Lin Lu; Ting Fan; Liyao Zheng; Jin-wu Yan; Dongxue Han; Li Niu

doi:10.1039/D4CC02977A

Construction of cationic meso-thiazolium-BODIPY AIE fluorescent probes for viscosity imaging in dual organelles†

Yu-Xin Tang,‡^a Yingmei Cao,‡^b Wen-Jing Shi,*^a Jin-Cheng Li,^a Wei-Lin Lu,^a Ting Fan,^a Liyao Zheng,

^a Jin-wu Yan,

*^b Dongxue Han

^a and Li Niu

*^a

Author affiliations

* Corresponding authors

^a Center for Advanced Analytical Science, Guangzhou Key Laboratory of Sensing Materials and Devices, Guangdong Engineering Technology Research Center for Photoelectric Sensing Materials and Devices, c/o School of Chemistry and Chemical Engineering, Guangzhou University, Guangzhou 510006, P. R. China
E-mail: swj114@gzhu.edu.cn, lniu@gzhu.edu.cn

^b School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, P. R. China
E-mail: yjw@scut.edu.cn

Abstract

Two new cationic meso-thiazolium-BODIPY-based water-soluble and red-shifted fluorescent probes were constructed for the first time. They can monitor cellular viscosity in dual organelles and show aggregation-induced emission (AIE), which is ascribed to the efficient restricted rotation of meso-thiazolium in viscous or hindered systems. Probe 3 with an N-benzyl group shows better AIE as compared to probe 2 with an N-methyl group.

Chemical Communications

Construction of cationic meso-thiazolium-BODIPY AIE fluorescent probes for viscosity imaging in dual organelles†

Abstract

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Construction of cationic meso-thiazolium-BODIPY AIE fluorescent probes for viscosity imaging in dual organelles

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