Issue 62, 2024
From the journal:

Chemical Communications

Design of a high-performance NIR-II nanoprobe by steric regulation for in vivo vasculature and tumor imaging†

Yu Wang,‡a   Yuxin Duan,‡a   Chenxing Gong,a   Yuhang Li,a   Meilin Xu,a   Miao Liu,b   Wenxu Liu,*a   Xiaole Zhou ORCID logo *a  and  Leyu Wang ORCID logo *a  

* Corresponding authors

a State Key Laboratory of Chemical Resource Engineering, College of Chemistry, Beijing University of Chemical Technology, Beijing 100029, P. R. China
E-mail: lywang@mail.buct.edu.cn, zhouxiaole@buct.edu.cn, liuwenxu@buct.edu.cn

b Department of Pharmacy, Northeast International Hospital Huanggu District, Shenyang, P. R. China

Abstract

A novel NIR-II nanoprobe was developed through regulating the steric effect of an A–DA′D–A dye. The probe features the properties of strong fluorescence, high stability, and a large Stokes shift, thereby serving as a remarkable contrast agent for the fluorescence imaging of hindlimb vasculature and tumors in live mice.

Graphical abstract: Design of a high-performance NIR-II nanoprobe by steric regulation for in vivo vasculature and tumor imaging

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Article information

DOI
https://doi.org/10.1039/D4CC02224F
Article type
Communication
Submitted
08 May 2024
Accepted
25 Jun 2024
First published
03 Jul 2024

Chem. Commun., 2024,60, 8059-8062

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Design of a high-performance NIR-II nanoprobe by steric regulation for in vivo vasculature and tumor imaging

Y. Wang, Y. Duan, C. Gong, Y. Li, M. Xu, M. Liu, W. Liu, X. Zhou and L. Wang, Chem. Commun., 2024, 60, 8059 DOI: 10.1039/D4CC02224F

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