Nanorotor R1 (420 kHz) was assembled from five components utilizing three orthogonal interactions. Post-modification at the distal position generated the advanced six component rotor R2 (45 kHz). The decrease in R2 speed leads to the inhibition of a three-component reaction by reducing catalyst release.
I. Paul, I. Valiyev, A. Ghosh and M. Schmittel, Chem. Commun., 2024, 60, 7085 DOI: 10.1039/D4CC02144D
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