Issue 70, 2024

Chemical synthesis of natural and azido-modified UDP-rhamnose and -arabinofuranose for glycan array-based characterization of plant glycosyltransferases

Abstract

Chemical syntheses of UDP-rhamnose and UDP-arabinofuranose and respective azido-modified analogues are reported. The prepared substrates are useful for the glycan array-based analysis of glycosyltransferases, as exemplified with the plant cell wall-biosynthetic enzymes PvXAT3, AtRRT4 and PtRRT5.

Graphical abstract: Chemical synthesis of natural and azido-modified UDP-rhamnose and -arabinofuranose for glycan array-based characterization of plant glycosyltransferases

Supplementary files

Article information

Article type
Communication
Submitted
30 Apr 2024
Accepted
26 Jul 2024
First published
29 Jul 2024

Chem. Commun., 2024,60, 9368-9371

Chemical synthesis of natural and azido-modified UDP-rhamnose and -arabinofuranose for glycan array-based characterization of plant glycosyltransferases

I. Pasini, C. Ruprecht, U. Osswald, A. Bittmann, L. Maltrovsky, C. Romanò, M. H. Clausen and F. Pfrengle, Chem. Commun., 2024, 60, 9368 DOI: 10.1039/D4CC02095B

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