G-quadruplex (G4) structures play roles in various biological processes, but the challenge lies in specific targeting. To address this, we synthesized a conjugate capable of recognizing the G4 structure and its proximal duplex. Our conjugate can enable recognition of specific G4s in the human genome to understand and target those structures.
M. Ooga, V. J. Sahayasheela, Y. Hirose, D. Sasaki, K. Hashiya, T. Bando and H. Sugiyama, Chem. Commun., 2024, 60, 8744 DOI: 10.1039/D4CC01572J
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