Issue 26, 2024
From the journal:

Chemical Communications

A Fe(iii) intercalated clay nanoplatform for combined chemo/chemodynamic therapy†

Ying Chen,abc   Jing Zhai,abc   Shiqi Wei,abc   Aidong Tang ORCID logo *abc  and  Huaming Yang ORCID logo *abc  

* Corresponding authors

a Engineering Research Center of Nano-Geomaterials of Ministry of Education, China University of Geosciences, Wuhan 430074, China
E-mail: tangaidong@cug.edu.cn, hm.yang@cug.edu.cn

b Faculty of Materials Science and Chemistry, China University of Geosciences, Wuhan 430074, China

c Laboratory of Advanced Mineral Materials, China University of Geosciences, Wuhan 430074, China

Abstract

A Fe(III) intercalated montmorillonite nanoplatform (Fe-MMT) was engineered for doxorubicin (DOX) loading. The constructed Fe-MMT/DOX nanoplatform could not only improve the production of H2O2 to enhance chemodynamic therapy but interfere with DNA damage repair to amplify the efficacy of DOX, proving an ideal combination of chemotherapy and chemodynamic therapy.

Graphical abstract: A Fe(iii) intercalated clay nanoplatform for combined chemo/chemodynamic therapy

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Article information

DOI
https://doi.org/10.1039/D3CC06205H
Article type
Communication
Submitted
21 Dec 2023
Accepted
01 Mar 2024
First published
01 Mar 2024

Chem. Commun., 2024,60, 3535-3538

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A Fe(III) intercalated clay nanoplatform for combined chemo/chemodynamic therapy

Y. Chen, J. Zhai, S. Wei, A. Tang and H. Yang, Chem. Commun., 2024, 60, 3535 DOI: 10.1039/D3CC06205H

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