Issue 1, 2024

Alternative protein encapsulation with MOFs: overcoming the elusive mineralization of HKUST-1 in water

Abstract

Protein encapsulation by in situ formation of MOFs is a valuable strategy to immobilise and protect these bioentities. However the required biocompatible conditions limits the scope of MOFs under investigation, particularly in the case of hydrolytically unstable MOFs such as HKUST-1. We report alternative synthetic procedures to obtain protein@HKUST-1 biocomposites from related Cu-BTC dense biocomposites. pH dependent dense phase precursors are first obtained and their transformations into HKUST-1 are characterized. Encapsulation efficiency is affected by the protein's nature, and can be modulated by the sequential or simultaneous addition of MOF precursors.

Graphical abstract: Alternative protein encapsulation with MOFs: overcoming the elusive mineralization of HKUST-1 in water

Supplementary files

Article information

Article type
Communication
Submitted
01 Sep 2023
Accepted
08 Nov 2023
First published
17 Nov 2023
This article is Open Access
Creative Commons BY-NC license

Chem. Commun., 2024,60, 51-54

Alternative protein encapsulation with MOFs: overcoming the elusive mineralization of HKUST-1 in water

J. C. Díaz and M. Giménez-Marqués, Chem. Commun., 2024, 60, 51 DOI: 10.1039/D3CC04320G

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. You can use material from this article in other publications, without requesting further permission from the RSC, provided that the correct acknowledgement is given and it is not used for commercial purposes.

To request permission to reproduce material from this article in a commercial publication, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party commercial publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements