The role of DNA nanotechnology in medical sensing

Abstract

This paper explores how DNA nanotechnology enhances biosensors in medicine and pharmacology by taking advantage of the unique characteristics of DNA and the unique advantages of DNA origami technology. DNA origami allows the establishment of complex nanoobjects with precise size and complete molecular writability as well as the possibility of seamless integration and biocompatibility with biological systems. Utilizing this, the chemical denaturation of DNA chains allows for the combination of various functions, including organic fluorescence groups and photoreaction elements, etc. This has allowed DNA origami to become a transformative tool in biotechnology and other fields because of its versatility, use in innovative applications improving the design and function of biosensors, and potential to provide greater possibilities for early disease diagnosis and personalized medicine.

Graphical abstract: The role of DNA nanotechnology in medical sensing

Article information

Article type
Technical Note
Submitted
04 Oct 2024
Accepted
21 Nov 2024
First published
06 Dec 2024
This article is Open Access
Creative Commons BY license

Anal. Methods, 2025, Advance Article

The role of DNA nanotechnology in medical sensing

D. Lien, Anal. Methods, 2025, Advance Article , DOI: 10.1039/D4AY01803F

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