Synthesis of indene in the liquid phase by a one-pot process using orthogonal tandem catalysis

Abstract

The one-pot synthesis of valuable indene from 1-indanone in the liquid phase was investigated using unassisted and assisted orthogonal tandem catalysis with a mechanical mixture of Cu/SiO₂ and HZSM-5. An indene yield of about 80% was achieved with assisted orthogonal tandem catalysis, varying the temperature and H₂ pressure during the process.