Copper borate (CuB4O7)-promoted multi-component green synthesis of 2,4,5-triarylimidazole derivatives and evidence of in situ conversion of copper borate (CuB4O7) into Cu(OAc)2 in the presence of NH4OAc

Abstract

A green, efficient, and straightforward methodology for the three-component synthesis of 2,4,5-triarylimidazole has been developed under solvent-free conditions using unconventional CuB₄O₇ as a promoter. This green approach encouragingly provides access to a library of 2,4,5-tri-arylimidazole. Also, we have been able to isolate the compound (5) and (6) in situ, which provides an insight into the direct conversion of CuB₄O₇ into copper acetate in the presence of NH₄OAc under solvent-free condition. The main advantage of this protocol includes an easy reaction procedure, short reaction time, and easy work up of the product without using any tedious separation method.