Issue 20, 2023

Celastraceae sesquiterpene pyridyl ligands


Celastraceae plant extracts have been widely used as traditional medicines and insecticides in China and South America. More recently, the extracts from Celastraceae plants have been studied at the molecular level and many of the interesting medicinal and agrochemical properties can be attributed to a large class of sesquiterpene alkaloids found in these extracts. These are generally based on highly oxygenated dihydroagarofuran cores with pyridyl diacid macrodilactone bridging ligands. Whereas previous reviews have focused on the dihydroagarofuran cores, in this article, the history, structure, and syntheses of the macrodilactone bridging ligands are reviewed.

Graphical abstract: Celastraceae sesquiterpene pyridyl ligands

Article information

Article type
Review Article
03 Jul 2023
30 Aug 2023
First published
31 Aug 2023
This article is Open Access
Creative Commons BY license

Org. Chem. Front., 2023,10, 5296-5308

Celastraceae sesquiterpene pyridyl ligands

C. Dai and A. C. Spivey, Org. Chem. Front., 2023, 10, 5296 DOI: 10.1039/D3QO01011B

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