Issue 25, 2023

Zinc-catalyzed transamidation and esterification of N-benzoyl cytosine via C–N bond cleavage

Abstract

We have utilized N-benzoyl cytosine for efficient transamidation and esterification via catalytic C–N bond cleavage. The one-pot strategy involves the reaction of secondary amide with various aliphatic or aromatic amines and alcohols in the presence of zinc triflate and DTBP, affording diverse amides and esters in excellent yields.

Graphical abstract: Zinc-catalyzed transamidation and esterification of N-benzoyl cytosine via C–N bond cleavage

Supplementary files

Article information

Article type
Communication
Submitted
04 May 2023
Accepted
05 Jun 2023
First published
06 Jun 2023

Org. Biomol. Chem., 2023,21, 5176-5180

Zinc-catalyzed transamidation and esterification of N-benzoyl cytosine via C–N bond cleavage

S. Gaware, R. Chatterjee, A. R. Kapdi and R. Dandela, Org. Biomol. Chem., 2023, 21, 5176 DOI: 10.1039/D3OB00697B

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