Issue 16, 2023

Bimodal structural tuning of pyrrole-2-carboxamide-based transmembrane ion transport systems

Abstract

The pyrrole-2-carboxamide moiety is well known for its presence in various natural products and its use in anion receptor systems. Here we assess the transmembrane anion transport activity of a series of substituted pyrrole-2-carboxamides and show them to be highly tuneable, versatile systems for anion transport by simple variations of pyrrole ring and amide substituents.

Graphical abstract: Bimodal structural tuning of pyrrole-2-carboxamide-based transmembrane ion transport systems

Supplementary files

Article information

Article type
Communication
Submitted
21 Feb 2023
Accepted
22 Mar 2023
First published
22 Mar 2023

Org. Biomol. Chem., 2023,21, 3323-3329

Bimodal structural tuning of pyrrole-2-carboxamide-based transmembrane ion transport systems

N. J. Roy, P. L. Pujari and P. Talukdar, Org. Biomol. Chem., 2023, 21, 3323 DOI: 10.1039/D3OB00269A

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