Issue 15, 2023

Preparation of an amphipathic polymer library in a mixture of water/ethanol by photoinduced polymerization and evaluation of the cryoprotective activity

Abstract

Synthetic cryoprotectants with macromolecular structures are desirable as alternatives to commonly used ones. Herein, we prepared an amphipathic polymer library and evaluated the cryoprotective ability of the polymers by facile screening using red blood cells. The cryoprotective properties of the amphipathic polymers was independent of both the log P values of the hydrophobic groups and the ice recrystallization inhibition activity.

Graphical abstract: Preparation of an amphipathic polymer library in a mixture of water/ethanol by photoinduced polymerization and evaluation of the cryoprotective activity

Supplementary files

Article information

Article type
Communication
Submitted
19 May 2023
Accepted
13 Jul 2023
First published
14 Jul 2023
This article is Open Access
Creative Commons BY-NC license

Mater. Adv., 2023,4, 3192-3196

Preparation of an amphipathic polymer library in a mixture of water/ethanol by photoinduced polymerization and evaluation of the cryoprotective activity

M. Nagao, S. Tanaka and Y. Miura, Mater. Adv., 2023, 4, 3192 DOI: 10.1039/D3MA00251A

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