A BODIPY-based fluorescent probe for simultaneous detection of H2O2 and viscosity during the pyroptosis process

Abstract

A dual functional BODIPY fluorescent probe was developed for simultaneous detection of H₂O₂ and viscosity, by collecting fluorescence from 800–1100 nm and 550–750 nm, respectively. Bioimaging based on the probe shows that H₂O₂ accumulates and cytoplasmic viscosity increases during the palmitic acid (PA)-induced pyroptosis process.