Issue 60, 2023

N-Fluorobenzenesulfonimide (NFSI) analogs with deprotectable substituents: synthesis of β-fluoroamines via catalytic aminofluorination of styrenes

Abstract

The palladium-catalyzed aminofluorination of styrenes using novel N-fluorobenzenesulfonimide (NFSI) derivatives with deprotectable substituents, and the selective deprotection and transformation of the resulting products into amines under mild reaction conditions are herein disclosed.

Graphical abstract: N-Fluorobenzenesulfonimide (NFSI) analogs with deprotectable substituents: synthesis of β-fluoroamines via catalytic aminofluorination of styrenes

Supplementary files

Article information

Article type
Communication
Submitted
11 May 2023
Accepted
21 Jun 2023
First published
23 Jun 2023

Chem. Commun., 2023,59, 9195-9198

N-Fluorobenzenesulfonimide (NFSI) analogs with deprotectable substituents: synthesis of β-fluoroamines via catalytic aminofluorination of styrenes

Y. Ito, A. Adachi, K. Aikawa, K. Nozaki and T. Okazoe, Chem. Commun., 2023, 59, 9195 DOI: 10.1039/D3CC02292G

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