Issue 28, 2023

A human VEGF magnetic molecularly imprinted polymer for drug-free anti-angiogenesis and photothermal therapy of tumors

Abstract

A magnetic molecularly imprinted polymer was developed with an epitope peptide of human VEGF as a template via an epitope blotting technique. As a drug-free agent, the nanoparticles can significantly suppress the proliferation of tumor cells by integrating anti-angiogenesis and photothermotherapy. This work provides a successful example of the design of multimodal antineoplastic drugs.

Graphical abstract: A human VEGF magnetic molecularly imprinted polymer for drug-free anti-angiogenesis and photothermal therapy of tumors

Supplementary files

Article information

Article type
Communication
Submitted
10 Jan 2023
Accepted
14 Mar 2023
First published
14 Mar 2023

Chem. Commun., 2023,59, 4229-4232

A human VEGF magnetic molecularly imprinted polymer for drug-free anti-angiogenesis and photothermal therapy of tumors

M. Wen, H. Shi, Y. Wan, J. Wu, X. Tian, Q. Chen, M. Wu and S. Feng, Chem. Commun., 2023, 59, 4229 DOI: 10.1039/D3CC00088E

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