A CaCO3-based synergistic immunotherapy strategy for treating primary and distal tumors

Kun Tang; Xia Zhang; Jiaqi Yin; Wei Pan; Yanhua Li; Na Li; Bo Tang

doi:10.1039/D2CC07076F

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A CaCO₃-based synergistic immunotherapy strategy for treating primary and distal tumors†

Kun Tang,

‡^a Xia Zhang,

‡^a Jiaqi Yin,

^a Wei Pan,

^a Yanhua Li,

*^a Na Li

*^a and Bo Tang

*^a

Author affiliations

* Corresponding authors

^a College of Chemistry, Chemical Engineering and Materials Science, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Institute of Molecular and Nano Science, Shandong Normal University, Jinan 250014, P. R. China
E-mail: liyanhua@sdnu.edu.cn, lina@sdnu.edu.cn, tangb@sdnu.edu.cn

Abstract

Low response rate limits the widespread application of cancer immunotherapy. To improve the response rate of immunotherapy, a CaCO₃-based composite nanomaterial was developed to induce immunogenic cell death for enhancing immunotherapy against 4T1 primary and distal tumors.

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Article information

DOI: https://doi.org/10.1039/D2CC07076F
Article type: Communication
Submitted: 30 Dec 2022
Accepted: 24 Feb 2023
First published: 25 Feb 2023

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Chem. Commun., 2023,59, 3562-3565

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A CaCO₃-based synergistic immunotherapy strategy for treating primary and distal tumors

K. Tang, X. Zhang, J. Yin, W. Pan, Y. Li, N. Li and B. Tang, Chem. Commun., 2023, 59, 3562 DOI: 10.1039/D2CC07076F

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Chemical Communications