Issue 19, 2023

NIR luminogen for low-temperature photothermal therapy by triggering HSP90α down-regulation

Abstract

A near-infrared (NIR) luminogen TST was designed and used to efficiently trigger HSP90α protein knockdown through photo-thermal conversion based on a gene interference strategy, by which in vitro and in vivo tumor ablation were significantly acquired at low-temperature.

Graphical abstract: NIR luminogen for low-temperature photothermal therapy by triggering HSP90α down-regulation

Supplementary files

Article information

Article type
Communication
Submitted
20 Dec 2022
Accepted
27 Jan 2023
First published
30 Jan 2023

Chem. Commun., 2023,59, 2743-2746

NIR luminogen for low-temperature photothermal therapy by triggering HSP90α down-regulation

X. Yang, K. Ding, G. Zhang, P. Han, R. Hu, Z. Wang, A. Qin and B. Z. Tang, Chem. Commun., 2023, 59, 2743 DOI: 10.1039/D2CC06932F

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