Issue 20, 2023
From the journal:

Chemical Communications

Synthesis of highly substituted isoquinolines/isoquinolones by ruthenium (ii)-catalyzed reaction of benzyl/α-methyl benzyl/benzoyl isocyanates with diaryl alkynes†

Amrendra Kumar,‡a   Shubham Jaiswal‡ab  and  Narender Tadigoppula ORCID logo *ab  

* Corresponding authors

a Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, Lucknow 226031, India
E-mail: t_narendra@cdri.res.in

b Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh-201 002, India

Abstract

An efficient and novel method has been developed for the synthesis of highly substituted isoquinolines/isoquinolones by Ru(II)-catalyzed intermolecular oxidative annulation of benzyl/benzoyl isocyanates with diaryl alkynes in the presence of Cs2CO3 as base and Cu(OTf)2 as an oxidant at 120 °C for 1 h.

Graphical abstract: Synthesis of highly substituted isoquinolines/isoquinolones by ruthenium (ii)-catalyzed reaction of benzyl/α-methyl benzyl/benzoyl isocyanates with diaryl alkynes

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/D2CC06165A
Article type
Communication
Submitted
14 Nov 2022
Accepted
07 Feb 2023
First published
20 Feb 2023

Chem. Commun., 2023,59, 2970-2973

Permissions

Request permissions

Synthesis of highly substituted isoquinolines/isoquinolones by ruthenium (II)-catalyzed reaction of benzyl/α-methyl benzyl/benzoyl isocyanates with diaryl alkynes

A. Kumar, S. Jaiswal and N. Tadigoppula, Chem. Commun., 2023, 59, 2970 DOI: 10.1039/D2CC06165A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements