Issue 36, 2023

A disposable and sensitive sensor based on a ZIF-8@graphene modified carbon paper electrode for the quantitative determination of luteolin

Abstract

Rapid and accurate determination of luteolin is of great significance for pharmaceutical quality control. Herein, a disposable and sensitive luteolin sensor was fabricated by a hydrothermal method with carbon paper as substrate where ZIF-8 grew on GR in situ. Notably, the large specific surface area of ZIF-8 provided active sites on the electrode surface and the ability of GR to promote electron transfer greatly improved the sensitivity towards the oxidation of luteolin. Under the optimum conditions, the ZIF-8@GR/CP showed excellent detection performance for luteolin with a linear detection range of 0.04–3.2 μM and 3.2–120 μM, with LOD of 12 nM (S/N = 3). Furthermore, this disposable and sensitive sensor was successfully applied for the quantitative detection of luteolin in a capsule of Lamiophlomis rotata.

Graphical abstract: A disposable and sensitive sensor based on a ZIF-8@graphene modified carbon paper electrode for the quantitative determination of luteolin

Supplementary files

Article information

Article type
Paper
Submitted
04 Jul 2023
Accepted
24 Aug 2023
First published
11 Sep 2023

Anal. Methods, 2023,15, 4736-4743

A disposable and sensitive sensor based on a ZIF-8@graphene modified carbon paper electrode for the quantitative determination of luteolin

W. Pang, Y. Gao, T. Hu and X. Ma, Anal. Methods, 2023, 15, 4736 DOI: 10.1039/D3AY01126G

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