Atomic-precise Pt2Cu4 cluster-based fluorescent sensor for rapid interleukin-6 detection

Zi-Hui Shao; Hui-Lin Mo; Xueli Zhao; Fuwei Xie; Ge Zhao

doi:10.1039/D3AY00642E

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Atomic-precise Pt₂Cu₄ cluster-based fluorescent sensor for rapid interleukin-6 detection†

Zi-Hui Shao,^a Hui-Lin Mo,^a Xueli Zhao,

*^a Fuwei Xie*^b and Ge Zhao^b

Author affiliations

* Corresponding authors

^a Henan Key Laboratory of Crystalline Molecular Functional Materials, Henan International Joint Laboratory of Tumor Theranostic Cluster Materials, Green Catalysis Center and College of Chemistry, Zhengzhou University, Zhengzhou 450001, China
E-mail: xuelizhao@zzu.edu.cn

^b Zhengzhou Tobacco Research Institute of CNTC, No. 2 of Fengyang Street, Zhengzhou, China
E-mail: xiefuwei@sina.com

Abstract

Levonorgestrel protected Pt₂Cu₄ clusters were assembled with a polymer to prepare nanobeads (NBs) with intense red fluorescence. An immunofluorescence sensor based on Pt₂Cu₄NBs was established for the rapid and sensitive detection of interleukin-6 (IL-6) owing to its significance in inflammatory diseases, with a limit of detection of 42.66 pg mL⁻¹. IL-6 spiked in serum was also accurately detected.

Download options Please wait...

Supplementary files

Supplementary information PDF (3061K)

Article information

DOI: https://doi.org/10.1039/D3AY00642E
Article type: Communication
Submitted: 27 Apr 2023
Accepted: 13 Jun 2023
First published: 14 Jun 2023

Download Citation

Anal. Methods, 2023,15, 3161-3164

Permissions

Request permissions

Atomic-precise Pt₂Cu₄ cluster-based fluorescent sensor for rapid interleukin-6 detection

Z. Shao, H. Mo, X. Zhao, F. Xie and G. Zhao, Anal. Methods, 2023, 15, 3161 DOI: 10.1039/D3AY00642E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Analytical Methods