Issue 43, 2022

Exploring the fluorescence enhancement of the split G-quadruplex towards DNA-templated AgNCs and their application in omethoate detection

Abstract

Herein, the fluorescent enhancement of the split G-quadruplex (G4) towards DNA-templated AgNCs (DNA-AgNCs) was systematically studied. It was shown that the two G-rich probes with the ratio of the guanine (G) bases of 6 : 6 was the best split mode, and the spacer length of the zero T base at both two sides could present the optimal distance between the AgNCs and split G4. In light of these results, a split G4 coupled with DNA-AgNCs for omethoate (OME) detection was successfully fabricated. The developed fluorescent aptasensor could sense OME in the concentration range of 5–200 nM with a detection limit of 4.16 nM. Moreover, the aptasensor performed well in real-sample detection.

Graphical abstract: Exploring the fluorescence enhancement of the split G-quadruplex towards DNA-templated AgNCs and their application in omethoate detection

Supplementary files

Article information

Article type
Communication
Submitted
17 Aug 2022
Accepted
15 Oct 2022
First published
17 Oct 2022

J. Mater. Chem. B, 2022,10, 8856-8861

Exploring the fluorescence enhancement of the split G-quadruplex towards DNA-templated AgNCs and their application in omethoate detection

L. Yin, H. Zhang, Y. Wang, L. He and L. Lu, J. Mater. Chem. B, 2022, 10, 8856 DOI: 10.1039/D2TB01755E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements