Nanoscale patterning of polymers on DNA origami†
The combination of DNA–origami and synthetic polymers paves the way to a new class of structurally precise biohybrid nanomaterials for diverse applications. Herein, we introduce the grafting to method with high conversions (70–90%) under ambient conditions to generate DNA–polymer conjugates, which can hybridized precisely to DNA–origami architectures. We generated homo and block copolymers from three different polymer families (acrylates, methacrylates and acrylamides), coupled them to single stranded DNA (ssDNA) and pattern different DNA–origami architectures to demonstrate the formation of precise surface nanopatterns.
- This article is part of the themed collections: Celebrating International Women’s Day: Women in Materials Science, Recent Open Access Articles, 2022 Journal of Materials Chemistry B Most Popular Articles and Journal of Materials Chemistry B Emerging Investigators