A copper-catalyzed four-component reaction of arylcyclopropanes, nitriles, carboxylic acids and N-fluorobenzenesulfonimide: facile synthesis of imide derivatives

Abstract

An unprecedented copper-catalyzed four-component reaction of arylcyclopropanes, nitriles, carboxylic acids and N-fluorobenzenesulfonimide (NFSI) has been successfully developed, which represents the first example of a four-component reaction of non-donor–acceptor cyclopropanes. A wide range of imide derivatives were efficiently synthesized in excellent yields under mild conditions.