Issue 15, 2022

Covalent organic frameworks and multicomponent reactions: an endearing give-and-take relationship

Abstract

Covalent organic frameworks (COFs) are porous and crystalline materials which are assembled from dynamic covalent bonds with two- or three-dimensional (2D or 3D) features. Unlike other polymers, COFs have significant and unique characteristics, including crystallinity, synthetic control, and structurally pre-designable aspects, among others. These notable intrinsic features render them an ideal platform energy conversion and storage, biomedical science, catalysis, sensing, separation, and adsorption applications. Solvothermal, sonochemical, ionothermal, microwave (MW), mechanochemical (MC) and multicomponent reaction (MCR) approaches are synthetic protocols that have been deployed for the construction of these fascinating materials. Herein, the most promising and relevant processing strategies are discussed for the formation of COFs via MCRs, highlighting the most important recent advances and encompassing the properties, characterization techniques, and production methods. A3-coupling, Povarov, Strecker, Groebke–Blackburn–Bienaymé, Debus–Radziszewski, and Doebner reactions are the MCRs that have been reported and summarized for the assembly of COFs. Furthermore, the successful usage of COFs to catalyze MCRs ranging from asymmetric synthesis to simple organic reactions is highlighted and discussed.

Graphical abstract: Covalent organic frameworks and multicomponent reactions: an endearing give-and-take relationship

Article information

Article type
Review Article
Submitted
02 May 2022
Accepted
17 Jun 2022
First published
21 Jun 2022

Org. Chem. Front., 2022,9, 4178-4191

Covalent organic frameworks and multicomponent reactions: an endearing give-and-take relationship

H. Yazdani, S. E. Hooshmand and R. S. Varma, Org. Chem. Front., 2022, 9, 4178 DOI: 10.1039/D2QO00697A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements