Decatungstate-photocatalyzed direct coupling of inert alkanes and quinoxalin-2(1H)-ones with H2 evolution

Abstract

A tetrabutylammonium decatungstate (TBADT)-photocatalyzed direct coupling of inert alkanes and quinoxalin-2(1H)-ones with H₂ evolution was developed at room temperature. The present transformation achieved direct C(sp³)–H/C(sp²)–H coupling under noble metal-free, acid-free and oxidant-free conditions. With this method, a series of 3-alkylated quinoxalin-2(1H)-ones bearing various functional groups were synthesized in good to excellent yields.