Probing the self-assembly and anti-glioblastoma efficacy of a cinnamoyl-capped dipeptide hydrogelator†
E. D.
Sitsanidis, 
ab
P. M.
Kasapidou,
ac
J. R.
Hiscock,
d
H.
Castel,
e
P. I. A.
Popoola,
d
A. J.
Hall
a
and
A. A.
Edwards
*a
ab
P. M.
Kasapidou,
ac
J. R.
Hiscock,
d
H.
Castel,
e
P. I. A.
Popoola,
d
A. J.
Hall
a
and
A. A.
Edwards
*a
Abstract
Herein, we introduce the first diphenylalanine dipeptide hydrogelator capped with the cinnamoyl functional group (Cin-L-F-L-F). We evaluate the effects of the cinnamoyl moiety on molecular self-assembly events and resultant physical properties of the hydrogel formed. In addition, we report our preliminary results of this dipeptide's cytotoxicity against glioblastoma (GBM) cancer cells.
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