Rh(iii)-Catalyzed ortho C–H functionalization of aromatic amides with bis(phenylsulfonyl)diazomethane and α-diazosulfones

Abstract

A Rh(III)-catalyzed migratory insertion of bis(phenylsulfonyl) carbene and α-sulfonyl carbenes into ortho C–H bonds of aryl amides has been developed. The products were obtained with moderate to excellent yields under mild reaction conditions. A reaction mechanism was proposed based on the control experiments and previous studies. Diverse desulfonylation transformations of the products were achieved.