Issue 4, 2022
From the journal:

Natural Product Reports

Natural withanolides, an update†

Gui-yang Xia,ab   Shi-jie Cao,a   Li-xia Chen ORCID logo *b  and  Feng Qiu ORCID logo *a  

* Corresponding authors

a School of Chinese Materia Medica, State Key Laboratory of Component-Based Chinese Medicine, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, Jinghai District, Tianjin, China
E-mail: fengqiu20070118@163.com

b Wuya College of Innovation, Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China
E-mail: syzyclx@163.com

Abstract

Covering: March 2010 to December 2020. Previous review: Nat. Prod. Rep., 2011, 28, 705

This review summarizes the latest progress and perspectives on the structural classification, biological activities and mechanisms, metabolism and pharmacokinetic investigations, biosynthesis, chemical synthesis and structural modifications, as well as future research directions of the promising natural withanolides. The literature from March 2010 to December 2020 is reviewed, and 287 references are cited.

Graphical abstract: Natural withanolides, an update

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Article information

DOI
https://doi.org/10.1039/D1NP00055A
Article type
Review Article
Submitted
24 Aug 2021
First published
24 Nov 2021

Nat. Prod. Rep., 2022,39, 784-813

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Natural withanolides, an update

G. Xia, S. Cao, L. Chen and F. Qiu, Nat. Prod. Rep., 2022, 39, 784 DOI: 10.1039/D1NP00055A

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