Issue 30, 2022

A novel fluorescent probe for the detection of Golgi nitroreductase under hypoxic conditions

Abstract

The first Golgi-targeted fluorescent probe (named Gol-NTR) for detecting nitroreductase (NTR) was developed. Gol-NTR had good selectivity for NTR and low cytotoxicity. Furthermore, it is worth noting that Gol-NTR was successfully applied to the detection of NTR in the Golgi apparatus, for the first time.

Graphical abstract: A novel fluorescent probe for the detection of Golgi nitroreductase under hypoxic conditions

Supplementary files

Article information

Article type
Communication
Submitted
12 May 2022
Accepted
08 Jul 2022
First published
08 Jul 2022

New J. Chem., 2022,46, 14333-14337

A novel fluorescent probe for the detection of Golgi nitroreductase under hypoxic conditions

Q. Zhang, Y. Tang, S. Song, J. Peng and W. Lin, New J. Chem., 2022, 46, 14333 DOI: 10.1039/D2NJ02326A

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