Issue 1, 2022

Droplet-assisted electrospray phase separation using an integrated silicon microfluidic platform

Abstract

We report a silicon microfluidic platform that enables monolithic integration of transparent micron-scale microfluidic channels, an on-chip segmentation of analyte flows into picoliter-volume droplets, and a nano-electrospray ionization emitter that enables spatial and temporal separation of oil and aqueous phases during electro-spray for subsequent mass spectrometry analysis.

Graphical abstract: Droplet-assisted electrospray phase separation using an integrated silicon microfluidic platform

Supplementary files

Article information

Article type
Communication
Submitted
26 Aug 2021
Accepted
01 Oct 2021
First published
12 Dec 2021
This article is Open Access
Creative Commons BY-NC license

Lab Chip, 2022,22, 40-46

Droplet-assisted electrospray phase separation using an integrated silicon microfluidic platform

Y. Zhang, S. Kim, W. Shi, Y. Zhao, I. Park, C. Brenden, H. Iyer, P. Jha, R. Bashir, J. V. Sweedler and Y. Vlasov, Lab Chip, 2022, 22, 40 DOI: 10.1039/D1LC00758K

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