Synthesis of β-fluorocarboxylic esters via organophotoredox-catalyzed fluoroalkoxycarbonylation of alkenes in EtOH

Abstract

An efficient and environmentally friendly organophotoredox-catalyzed method for the synthesis of β-fluorocarboxylic esters with a broad substrate scope in EtOH has been developed. With this approach, a variety of potential biologically active molecules containing both fluorine and ester functionalities have been prepared.