Issue 12, 2022

Visible-light-driven multicomponent reactions to access S-alkyl phosphorothioates using elemental sulfur as the sulfur source

Abstract

A metal-free and unprecedented strategy has been established for the construction of S-alkyl phosphorothioates through visible-light-driven four-component reactions of α-diazoesters, cyclic ethers, elemental sulfur and H-phosphonates. This strategy simply utilizes DBU as additive and elemental sulfur as the cheap and odorless sulfur source, providing an efficient and attractive approach to access various S-alkyl phosphorothioates under mild conditions. Notably, three-component coupling products of α-diazoesters, elemental sulfur, and H-phosphonates could also be conveniently obtained in moderate to good yields by simply changing the reaction solvent.

Graphical abstract: Visible-light-driven multicomponent reactions to access S-alkyl phosphorothioates using elemental sulfur as the sulfur source

Supplementary files

Article information

Article type
Paper
Submitted
08 Mar 2022
Accepted
23 May 2022
First published
31 May 2022

Green Chem., 2022,24, 4915-4920

Visible-light-driven multicomponent reactions to access S-alkyl phosphorothioates using elemental sulfur as the sulfur source

C. Qu, R. Liu, Z. Wang, Y. Lv, H. Yue and W. Wei, Green Chem., 2022, 24, 4915 DOI: 10.1039/D2GC00903J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements