Issue 78, 2022

An endoperoxide-containing covalent organic framework as a singlet oxygen reservoir for cancer therapy

Abstract

A porphyrin-based COF containing a dialkylnaphthalene derivative was constructed to deliver extracellular singlet oxygen (1O2) into cancer cells through the Diels–Alder/retro-Diels–Alder reaction between dialkylnaphthalene and 1O2 to realize light- and oxygen-independent oxidative damage for cancer therapy.

Graphical abstract: An endoperoxide-containing covalent organic framework as a singlet oxygen reservoir for cancer therapy

Supplementary files

Article information

Article type
Communication
Submitted
19 Jul 2022
Accepted
30 Aug 2022
First published
01 Sep 2022

Chem. Commun., 2022,58, 11013-11016

An endoperoxide-containing covalent organic framework as a singlet oxygen reservoir for cancer therapy

F. Lu, L. Pan, T. Wu, W. Pan, W. Gao, N. Li and B. Tang, Chem. Commun., 2022, 58, 11013 DOI: 10.1039/D2CC04026C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements