Issue 46, 2022

Water-soluble AIE-active fluorescent organic nanoparticles for ratiometric detection of SO2 in the mitochondria of living cells

Abstract

We report a water-soluble AIEgen (TYDL) to be self-assembled into fluorescent organic nanoparticles (TYDLs) for specific sensing of SO2 in living hepatoma cells. It is demonstrated that the TYDLs were suitable for ratiometrically detecting endogenous and exogenous SO2 in mitochondria with good selectivity, low detection limit (75 nM) and excellent photostability (>30 min). These findings imply the great potential applications of TYDLs for the diagnosis of SO2-related diseases in cell biology.

Graphical abstract: Water-soluble AIE-active fluorescent organic nanoparticles for ratiometric detection of SO2 in the mitochondria of living cells

Supplementary files

Article information

Article type
Communication
Submitted
16 Apr 2022
Accepted
10 May 2022
First published
10 May 2022

Chem. Commun., 2022,58, 6618-6621

Water-soluble AIE-active fluorescent organic nanoparticles for ratiometric detection of SO2 in the mitochondria of living cells

G. Feng, Y. Liu, Y. Ji, W. Zhou, X. Li, M. Hou, J. Gao, Y. Zhang and G. Xing, Chem. Commun., 2022, 58, 6618 DOI: 10.1039/D2CC02168D

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