Issue 34, 2022
From the journal:

Chemical Communications

A covalent organic framework with a self-contained light source for photodynamic therapy†

Wen-Xiu Ren,‡a   Fei Kong,‡a   Yu-Qing Shao,a   Qing-Yun Huang,a   Long-Fei Sun,a   Jie Feng ORCID logo *a  and  Yu-Bin Dong ORCID logo *a  

* Corresponding authors

a College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education Shandong Normal University, Jinan 250014, People's Republic of China
E-mail: Jiefeng@sdnu.edu.cn, yubindong@sdnu.edu.cn

Abstract

External light-independent antitumor PDT is successfully realized with a covalent organic framework (COF)-based host–guest nanosystem. Its highly effective antitumor behavior is fully demonstrated by both H2O2-overexpressed 4T1 and H2O2-less expressed HCT116 and MCF-7 xenograft models.

Graphical abstract: A covalent organic framework with a self-contained light source for photodynamic therapy

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Article information

DOI
https://doi.org/10.1039/D2CC01397E
Article type
Communication
Submitted
09 Mar 2022
Accepted
29 Mar 2022
First published
30 Mar 2022

Chem. Commun., 2022,58, 5245-5248

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A covalent organic framework with a self-contained light source for photodynamic therapy

W. Ren, F. Kong, Y. Shao, Q. Huang, L. Sun, J. Feng and Y. Dong, Chem. Commun., 2022, 58, 5245 DOI: 10.1039/D2CC01397E

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