Issue 14, 2022
From the journal:

Chemical Communications

A CuS- and BODIPY-loaded nanoscale covalent organic framework for synergetic photodynamic and photothermal therapy†

Xiao-Jie Dong,‡a   Wen-Yan Li,‡a   Qun Guan, ORCID logo a   Yan-An Li ORCID logo *a  and  Yu-Bin Dong ORCID logo *a  

* Corresponding authors

a College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Normal University, Jinan 250014, P. R. China
E-mail: yananli@sdnu.edu.cn, yubindong@sdnu.edu.cn

Abstract

Herein, we report an inorganic photothermal agent, CuS- and an organic photosensitizer, BODIPY-loaded composite nanoscale COF material via a stepwise post-synthetic modification. The obtained CuS@COF-BDP can be a dual-modal therapeutic agent to highly inhibit MCF-7 tumor cell proliferation due to its efficient singlet oxygen generation and photothermal conversion abilities.

Graphical abstract: A CuS- and BODIPY-loaded nanoscale covalent organic framework for synergetic photodynamic and photothermal therapy

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Article information

DOI
https://doi.org/10.1039/D1CC06330H
Article type
Communication
Submitted
10 Nov 2021
Accepted
17 Jan 2022
First published
18 Jan 2022

Chem. Commun., 2022,58, 2387-2390

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A CuS- and BODIPY-loaded nanoscale covalent organic framework for synergetic photodynamic and photothermal therapy

X. Dong, W. Li, Q. Guan, Y. Li and Y. Dong, Chem. Commun., 2022, 58, 2387 DOI: 10.1039/D1CC06330H

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