A novel FRET-based dendritic hybridization chain reaction for tumour-related mRNA imaging

Shiyuan Liu; Zhenxiang Liu; Huimin Wang; Jiaoli Wang; Ruiting Liu; Kemin Wang; Jin Huang

doi:10.1039/D1CC06009K

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A novel FRET-based dendritic hybridization chain reaction for tumour-related mRNA imaging†

Shiyuan Liu,^a Zhenxiang Liu,^a Huimin Wang,^a Jiaoli Wang,^a Ruiting Liu,^a Kemin Wang

^a and Jin Huang

*^a

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* Corresponding authors

^a State Key Laboratory of Chemo/Biosensing and Chemometrics, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Hunan University, Changsha, China
E-mail: jinhuang@hnu.edu.cn

Abstract

A novel FRET-based dendritic hybridization chain reaction (D-HCR) for TK1 mRNA imaging in living cells was developed. Compared with traditional complex D-HCR methods, it includes the advantages of having a simple design, an accurate signal and is suitable for use with living cells.

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Article information

DOI: https://doi.org/10.1039/D1CC06009K
Article type: Communication
Submitted: 25 Oct 2021
Accepted: 21 Dec 2021
First published: 22 Dec 2021

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Chem. Commun., 2022,58, 1414-1417

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A novel FRET-based dendritic hybridization chain reaction for tumour-related mRNA imaging

S. Liu, Z. Liu, H. Wang, J. Wang, R. Liu, K. Wang and J. Huang, Chem. Commun., 2022, 58, 1414 DOI: 10.1039/D1CC06009K

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Chemical Communications

A novel FRET-based dendritic hybridization chain reaction for tumour-related mRNA imaging†

Abstract

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A novel FRET-based dendritic hybridization chain reaction for tumour-related mRNA imaging

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