Controllable signal molecule release from Au NP-gated MSNs for photocathodic detection of ultralow level AβO†
Abstract
By integrating a target-responsive MSN-based controlled release system with a sensitization-SPR co-enhanced thionine/MoS2 QDs/Cu NWs photocathode, a highly sensitive split-type PEC aptasensing platform for AβO detection in blood is constructed. Ultralow detection limit (2.1 fM) and high selectivity show great potential in early AD diagnosis.

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