Issue 13, 2022
From the journal:

Chemical Communications

Aerobic oxidation of aldehydes to acids in water with cyclic (alkyl)(amino)carbene copper under mild conditions†

Songbo Xu,ab   Xiaomin Zhang, ORCID logo *ac   Wenjie Xiong, ORCID logo a   Ping Li,a   Wentao Ma,a   Xingbang Hu ORCID logo *ac  and  Youting Wu*ac  

* Corresponding authors

a School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, P. R. China
E-mail: xmzhang@nju.edu.cn, huxb@nju.edu.cn, ytwu@nju.edu.cn

b Shandong Kanbo Biochemical Technology Co., Ltd, Dongying, P. R. China

c Yuxiu Postdoctoral Institute, Nanjing University, Nanjing 210023, P. R. China

Abstract

In this work, cyclic (alkyl)(amino)carbene copper ((CAAC)Cu) catalyzed aerobic oxidation of aldehydes in water at room temperature has been reported. Good to excellent yields were obtained using different substrates. A possible reaction mechanism was proposed, in which (CAAC)Cu dioxygen activates the C–H bond of aldehyde with a low barrier of 10.6 kcal mol−1.

Graphical abstract: Aerobic oxidation of aldehydes to acids in water with cyclic (alkyl)(amino)carbene copper under mild conditions

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/D1CC04812K
Article type
Communication
Submitted
29 Aug 2021
Accepted
18 Oct 2021
First published
19 Oct 2021

Chem. Commun., 2022,58, 2132-2135

Permissions

Request permissions

Aerobic oxidation of aldehydes to acids in water with cyclic (alkyl)(amino)carbene copper under mild conditions

S. Xu, X. Zhang, W. Xiong, P. Li, W. Ma, X. Hu and Y. Wu, Chem. Commun., 2022, 58, 2132 DOI: 10.1039/D1CC04812K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements