Depth prediction of nanotags in tissue using surface enhanced spatially offset Raman scattering (SESORS)

Matthew E. Berry; Samantha M. McCabe; Neil C. Shand; Duncan Graham; Karen Faulds

doi:10.1039/D1CC04455A

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Depth prediction of nanotags in tissue using surface enhanced spatially offset Raman scattering (SESORS)†‡

Matthew E. Berry,

^a Samantha M. McCabe,

^a Neil C. Shand,

^b Duncan Graham

^a and Karen Faulds

*^a

Author affiliations

* Corresponding authors

^a Centre for Molecular Nanometrology, Department of Pure and Applied Chemistry, University of Strathclyde, 99 George Street, Glasgow, UK
E-mail: karen.faulds@strath.ac.uk

^b Defence Science and Technology Laboratory (DSTL), Porton Down, Salisbury, UK

Abstract

A model for the prediction of the depth of two ‘flavours’ of surface enhanced Raman scattering (SERS) active nanotags embedded within porcine tissue is demonstrated using ratiometric analysis. Using a handheld spatially offset Raman (SORS) instrument, SESORS signals could be detected from nanotags at depths down to 48 mm for the first time using a backscattering SORS geometry.

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Article information

DOI: https://doi.org/10.1039/D1CC04455A
Article type: Communication
Submitted: 13 Aug 2021
Accepted: 04 Jan 2022
First published: 14 Jan 2022
This article is Open Access

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Chem. Commun., 2022,58, 1756-1759

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Depth prediction of nanotags in tissue using surface enhanced spatially offset Raman scattering (SESORS)

M. E. Berry, S. M. McCabe, N. C. Shand, D. Graham and K. Faulds, Chem. Commun., 2022, 58, 1756 DOI: 10.1039/D1CC04455A

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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Chemical Communications

Depth prediction of nanotags in tissue using surface enhanced spatially offset Raman scattering (SESORS)†‡

Abstract

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Depth prediction of nanotags in tissue using surface enhanced spatially offset Raman scattering (SESORS)

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