Issue 5, 2022

A fully integrated sample preparation strategy for highly sensitive intact glycoproteomics

Abstract

A fully integrated sample preparation technology, termed Intact GlycoSISPROT, was developed for the highly sensitive analysis of site-specific glycopeptides. Through integrating all glycoproteomic sample preparation steps into a single spintip, Intact GlycoSISPROT provided a tool for site-specific glycosylation analysis with low micrograms to even nanograms of protein sample.

Graphical abstract: A fully integrated sample preparation strategy for highly sensitive intact glycoproteomics

Supplementary files

Article information

Article type
Communication
Submitted
30 Nov 2021
Accepted
21 Jan 2022
First published
21 Jan 2022

Analyst, 2022,147, 794-798

A fully integrated sample preparation strategy for highly sensitive intact glycoproteomics

L. Yang, J. Liu, H. Li, Y. Liu, A. He, P. Huang, W. Gao, H. Cao, R. Xu and R. Tian, Analyst, 2022, 147, 794 DOI: 10.1039/D1AN02166D

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