Issue 18, 2021

A pair of particles in inertial microfluidics: effect of shape, softness, and position

Abstract

Lab-on-a-chip devices based on inertial microfluidics have emerged as a promising technique to manipulate particles in a precise way. Inertial microfluidics exploits internal hydrodynamic forces and the mechanical structure of particles to achieve separation and focusing. The article focuses on the hydrodynamic interaction of two particles. This will help to develop an understanding of the dynamics of particle trains in inertial microfluidics, which are typical structures in multi-particle systems. We perform three-dimensional lattice Boltzmann simulations combined with the immersed boundary method to unravel the dynamics of various mono- and bi-dispersed pairs in inertial microfluidics. We study the influence of different starting positions for mono- and bi-dispersed pairs. We also change their deformability from relatively soft to rigid and choose spherical and biconcave particle shapes. The observed two-particle motions in the present work can be categorized into four types: stable pair, stable pair with damped oscillations, stable pair with bounded oscillations, and unstable pair. We show that stable pairs become unstable when increasing the particle stiffness. Furthermore, a pair with both capsules in the same channel half is more prone to become unstable than a pair with capsules in opposite channel halves.

Graphical abstract: A pair of particles in inertial microfluidics: effect of shape, softness, and position

Supplementary files

Article information

Article type
Paper
Submitted
22 Feb 2021
Accepted
09 Apr 2021
First published
19 Apr 2021
This article is Open Access
Creative Commons BY license

Soft Matter, 2021,17, 4804-4817

A pair of particles in inertial microfluidics: effect of shape, softness, and position

K. Patel and H. Stark, Soft Matter, 2021, 17, 4804 DOI: 10.1039/D1SM00276G

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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