Issue 56, 2021
From the journal:

RSC Advances

Deep-red fluorogenic cyanine dyes carrying an amino group-terminated side chain for improved RNA detection and nucleolar RNA imaging†

Yusuke Sato, ORCID logo *a   Yugo Igarashi,a   Michiyuki Suzuki,a   Kei Higuchia  and  Seiichi Nishizawa ORCID logo *a  

* Corresponding authors

a Department of Chemistry, Graduate School of Science, Tohoku University, Aoba-ku, Sendai 980-8578, Japan
E-mail: yusuke.sato.a7@tohoku.ac.jp, seiichi.nishizawa.c8@tohoku.ac.jp
Fax: +81-22-795-6552
Tel: +81-22-795-6549

Abstract

The introduction of an amino-group-terminated side chain into deep-red emissive benzo[c,d]indole–quinoline monomethine cyanine dye has led to the improved detection of RNAs as well as the imaging of nucleolar RNAs in cells.

Graphical abstract: Deep-red fluorogenic cyanine dyes carrying an amino group-terminated side chain for improved RNA detection and nucleolar RNA imaging

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Article information

DOI
https://doi.org/10.1039/D1RA05872J
Article type
Paper
Submitted
03 Aug 2021
Accepted
22 Oct 2021
First published
17 Nov 2021
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2021,11, 35436-35439

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Deep-red fluorogenic cyanine dyes carrying an amino group-terminated side chain for improved RNA detection and nucleolar RNA imaging

Y. Sato, Y. Igarashi, M. Suzuki, K. Higuchi and S. Nishizawa, RSC Adv., 2021, 11, 35436 DOI: 10.1039/D1RA05872J

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