Issue 24, 2021

A selective and sensitive near-infrared fluorescent probe for real-time detection of Cu(i)

Abstract

The disruption of copper homeostasis (Cu+/Cu2+) may cause neurodegenerative disorders. Thus, the need for understanding the role of Cu+ in physiological and pathological processes prompted the development of improved methods of Cu+ analysis. Herein, a new near-infrared (NIR) fluorescent turn-on probe (NPCu) for the detection of Cu+ was developed based on a Cu+-mediated benzylic ether bond cleavage mechanism. The probe showed high selectivity and sensitivity toward Cu+, and was successfully applied for bioimaging of Cu+ in living cells.

Graphical abstract: A selective and sensitive near-infrared fluorescent probe for real-time detection of Cu(i)

Supplementary files

Article information

Article type
Paper
Submitted
27 Jan 2021
Accepted
26 Mar 2021
First published
21 Apr 2021
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2021,11, 14824-14828

A selective and sensitive near-infrared fluorescent probe for real-time detection of Cu(I)

Y. Liu, T. Kang, Q. He, Y. Hu, Z. Zuo, Z. Cao, B. Ke, W. Zhang and Q. Qi, RSC Adv., 2021, 11, 14824 DOI: 10.1039/D1RA00725D

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