Issue 22, 2021, Issue in Progress
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RSC Advances

An ionic liquid–molecularly imprinted composite based on graphene oxide for the specific recognition and extraction of cancer antigen 153

Shuang Han, ORCID logo *ab   Aixin Yaoa  and  Yuan Wangc  

* Corresponding authors

a College of Chemistry and Chemical Engineering, Qiqihar University, Qiqihar, China

b Heilongjiang Provincial Key Laboratory of Catalytic Synthesis for Fine Chemicals, Qiqihar University, Qiqihar, China

c Heilongjiang Province Qiqihar Ecological Environment Monitoring Center, Qiqihar, China

Abstract

Molecularly imprinted polymers with graphene oxide (GO) as a carrier (GMIPs) were synthesized to selectively recognize and capture cancer antigen 153 (CA153). The results show that the MIP has good selectivity and adsorption for CA153, and has strong anti-interference ability. Molecularly imprinted solid phase extraction (MISPE) combined with ultra performance liquid chromatography (UPLC) for the specific adsorption of CA153 was also established, and showed great potential for the analysis of CA153 in clinics in the future.

Graphical abstract: An ionic liquid–molecularly imprinted composite based on graphene oxide for the specific recognition and extraction of cancer antigen 153

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Article information

DOI
https://doi.org/10.1039/D1RA00134E
Article type
Paper
Submitted
07 Jan 2021
Accepted
14 Mar 2021
First published
07 Apr 2021
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2021,11, 13085-13090

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An ionic liquid–molecularly imprinted composite based on graphene oxide for the specific recognition and extraction of cancer antigen 153

S. Han, A. Yao and Y. Wang, RSC Adv., 2021, 11, 13085 DOI: 10.1039/D1RA00134E

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